Rheumatoid arthritis–associated autoantibodies (RA-AAB) can be present in serum years before clinical onset of rheumatoid arthritis (RA). It has been hypothesized that initiation of RA-AAB generation occurs at inflamed mucosal surfaces, such as in the oral cavity or lungs. The aim of this study was to assess systemic presence of RA-AAB in patients without RA who had oral or lung mucosal inflammation.
Via Krishan Maggon
Arthritis Research & Therapy 2015, 17:174
doi:10.1186/s13075-015-0690-6
Koen M J Janssen1†, Menke J de Smit2†, Elisabeth Brouwer3, Fenne A C de Kok3, Jan Kraan4, Josje Altenburg5, Marije K Verheul6, Leendert A Trouw6, Arie Jan van Winkelhoff27, Arjan Vissink1 and Johanna Westra3*
*Corresponding author: Johanna Westra johanna.westra@umcg.nl